Abnormal lipid metabolism in fat cells predicts future weight gain and diabetes in women
The inefficient breakdown of fats foretells later metabolic complications such as type 2 diabetes in women and weight gain. Low levels of hormone-stimulated lipolysis -- a biochemical process by which triglycerides (Cholesterol, lipid) are broken down into energy-rich fatty acids -- were related with weight gain and metabolic problems in future. To detect impedances in hormone-stimulated lipolysis , researchers created an algorithm using clinical and blood measures. Researchers believed that their proposed algorithm could be helpful in identifying subjects with a high risk of becoming overweight or obese. These findings may well be utilized by clinicians to determine who would benefit the most from intensified lifestyle interventions such as physical activity, which improves hormone-stimulated lipolysis and may therefore prevent metabolic disturbances and fat accumulation. Researchers took biopsies of subcutaneous fat tissue from healthy and non-obese 89 women, and followed up 1...